C57BL/6 mice underwent retrograde infusion of taurocholate into the pancreatic duct.
In the present study, we studied the role of extracellular cold-inducible RNA-binding protein (eCIRP), a novel damage-associated-molecular-pattern molecule, in severe AP. Neutrophil extracellular traps (NETs) play a key role in the development of acute pancreatitis (AP).